Tag Archives: RMIT University

Eureka Prize Winners of 2016

Featured image above: Winners of the 2016 UNSW Eureka Prize for Scientific Research, Melissa Little and Minoru Takasato from the Murdoch Childrens Research Institute. Credit: Australian Museum

Regenerating kidneys, smart plastics, artificial memory cells and a citizen science network that tracks falling meteors. These and many other pioneering scientific endeavours have been recognised in the 2016 annual Australian Museum Eureka Prizes, awarded at a gala dinner in Sydney.

Having trouble with a kidney? It may not be long before you can simply grow a new one. This is the ultimate ambition behind the research of the 2016 UNSW Eureka Prize for Scientific Research winners, which was awarded to Melissa Little and Minoru Takasato from the Murdoch Childrens Research Institute.

They have developed a method of growing kidney tissue from stem cells, and their kidney “organoids” develop all the different types of cells that are needed for kidney function. The kidney tissue is currently used in the lab to model kidney disease and to test new drugs, but one day the technique could be developed to regrow replacement kidneys for transplant.

For his work using the latest in 3D printing and materials technology develop a world centre for electromaterials science, Gordon Wallace, from the University of Wollongong, received the 2016 CSIRO Eureka Prize for Leadership in Innovation and Science.

Some of the materials he and his team are developing include structures that are biocompatible, meaning they can be used inside the body without causing an adverse reaction. These structures can be used to promote muscle and nerve cell growth. Other cells include artificial muscles using carbon nanotubes.

The CSIRO’s Lisa Harvey-Smith has been one of the most vocal and energetic proponents of science in the media and the general public, especially amongst Indigenous communities. It is for her work as the face of the Australian Square Kilometre Array Pathfinder (ASKAP) and communicating astronomy to the public that Harvey-Smith was awarded the 2016 Department of Industry, Innovation and Science Eureka Prize for Promoting Understanding of Australian Science.

Have you ever seen a meteor streak across the sky and wondered where it landed? Phil Bland, from Curtin University, certainly hopes you have. He and his team set up the Desert Fireball Network, which allows members of the public to track meteors as they fall, helping them to identify where they land, and where they came from.

For this, Bland and his team were awarded the 2016 Department of Industry, Innovation and Science Eureka Prize for Innovation in Citizen Science.

But not all the awards went to seasoned researchers. Some were reserved for the next generation of scientific pioneers.

Hayden Ingle, a Grade 6 student from Banksmeadow Primary School in Botany, received the 2016 Sleek Geeks Science Eureka Prize for Primary Schools for his video production, The Bluebottle and the Glaucus. It tells the remarkable tale of a little known sea predator, the tiny sea lizard, or glacus atlantica, and its fascinating relationship with the bluebottle.

Speaking of predators, a video by Claire Galvin and Anna Hardy, Year 10 students at St Monica’s College, Cairns, won the 2016 Sleek Geeks Science Eureka Prize for Secondary Schools for exploring the eating habits of the Barn Owl.

They examined “owl pellets”, which contain the indigestible components of the owl’s last meal, and used them to identify its prey.

Other winners of the 2016 Eureka Prize

Ewa Goldys from Macquarie University and the ARC Centre of Excellence for Nanoscale BioPhotonics and Martin Gosnell from Quantitative Pty Ltd have been awarded the ANSTO Eureka Prize for Innovative Use of Technology for their development of hyperspectral imaging technology, which enables the colour of cells and tissues to be used as a non-invasive medical diagnostic tool.

For his discovery and development of novel treatments for serious brain disorders, Michael Bowen, from the University of Sydney, is the winner of the Macquarie University Eureka prize for Outstanding Early Career Researcher. His research has established oxytocin and novel molecules that target the brain’s oxytocin system as prime candidates to fill the void left by the lack of effective treatments for alcohol-use disorders and social disorders.

For developing a new generation of armoured vehicles to keep Australian soldiers safe in war zones, Thales Australia and Mark Brennan have won the 2016 Defence Science and Technology Eureka Prize for Outstanding Science in Safeguarding Australia.

Davidson Patricia Davidson is Dean of the Johns Hopkins University School of Nursing in Maryland, and has mentored more than 35 doctoral and postdoctoral researchers, working tirelessly and with passion to build the capacity of early career researchers, an achievement that has won her the 2016 University of Technology Sydney Eureka Prize for Outstanding Mentor of Young Researchers.

For taking basic Australian research discoveries and developing them into a new cancer therapy that was approved by the US Food and Drug Administration in April this year, David Huang and his team from the Walter and Eliza Hall Institute of Medical Research has win the 2016 Johnson & Johnson Eureka Prize for Innovation in Medical Research. The drug, venetoclax, was approved for a high-risk sub-group of patients with Chronic Lymphocytic Leukemia and is now marketed in the US.

For creating a three part documentary that portrayed both the good and the evil of uranium in a series seen around the world, Twisting the Dragon’s Tail, Sonya Pemberton, Wain Fimeri and Derek Muller, won the 2016 Department of Industry, Innovation and Science Eureka Prize for Science Journalism.

Sharath Sriram, Deputy Director of the A$30 million Micro Nano Research Facility at RMIT University, has won the 2016 3M Eureka Prize for Emerging Leader in Science for his extraordinary career – during which he and his team have developed the world’s first artificial memory cell that mimics the way the brain stores long term memory.

For bringing together a team with skills ranging from mathematical modelling to cell biology and biochemistry, Leann Tilley and her team from the University of Melbourne have won the 2016 Australian Infectious Diseases Research Centre Eureka Prize for Infectious Disease Research. They have uncovered an important life saving mechanism by which the malaria parasite has developed resistance to what has been previously a widely used and successful malarial treatment.

For recruiting an international team of scientists to measure trace elements in the oceans from 3.5 billion years ago to the present day to understand the events that led to the evolution of life and extinction of life in the oceans, Ross Large from the University of Tasmania and researchers from as far as Russia and the US have won the 2016 Eureka Prize for Excellence in Interdisciplinary Research.

For conducting the world’s first survey of plastic pollutants which has given us a confronting snapshot of the impacts on marine wildlife of the 8.4 million tones of plastic that enters the oceans each year, Denise Hardesty, Chris Wilcox, Tonya Van Der Velde, TJ Lawson, Matt Landell and David Milton from CSIRO in Tasmania and Queensland have won the 2016 NSW Office of Environment and Heritage Eureka Prize for Environmental Research.

The Functional Annotation of the Mammalian Genome (FANTOM5) project produced a map that is being used to interpret genetic diseases and to engineer new cells for therapeutic use. The team led by Alistair Forrest from the Harry Perkins Institute of Medical Research has won the 2016 Scopus Eureka Excellence in International Scientific Collaboration Prize.

– Tim Dean

This article on the Eureka Prize 2016 winners was first published by The Conversation on 31 August 2016. Read the original article here.

Smart Contact Lens

The University of Adelaide in South Australia worked closely with RMIT University to develop small hi-tech lenses to filter harmful optical radiation without distorting vision.

Dr Withawat Withayachumnankul from the University of Adelaide helped conceive the idea and says the potential applications of the technology included creating new high-performance devices that connect to the internet.

“With advanced techniques to control the properties of surfaces, we can dynamically control their filter properties, which allow us to potentially create devices for high data rate optical communication or smart contact lenses,” he says.

“There is also the potential for it to have Wi-Fi access points and connection to external devices.”

The small lenses could also be used to gather and transmit information on a small display.

While there are numerous possible applications of the device, Withayachumnankul says the original purpose of the lens was an alternative to radiation protective goggles.

“We used a stretchable material called PDMS (Polydimethylsiloxane) and put some nano-material structures inside that layer which interacts with light,” he says.

“The functionality of the device is that the lens filters the light while maintaining a fully transparent structure, and can protect the eyes from radiation.”

Tiny artificial crystals termed “dielectric resonators” were used to help manipulate the waves of light.

The resonators are a fraction of the wavelength of light (100–500 nanometres) and are 500 times thinner than human hair.

“The current challenge is that the dielectric resonators only work for specific colours, but with our flexible surface we can adjust the operation range simply by stretching it,” Withayachumnankul says.

The materials used to make the lens have proven to be biocompatible and do not create any irritation to the eyes, making the device safe to wear.

Findings of the research were published in leading nano-science journal ACS Nano and were undertaken at RMIT’s Micro Nano Research Facility.

The discovery comes after scientists from the University of South Australia’s Future Industries Institute this month successfully completed “proof of concept” research on a polymer film coating that conducts electricity on a contact lens, with the potential to build miniature electrical circuits that are safe to be worn by a person.

– Caleb Radford

This article was first published by The Lead on 19 February 2016. Read the original article here.

Medical device could save lives

An award-winning medical device could save lives. The ECGx/Medibase system, developed by the Medical Engineering Database Solutions (MEDS) team of students from RMIT University in Melbourne, is a groundbreaking technology used in ambulances to allow a patient’s electrocardiogram (ECG) information to be shared with doctors at the hospital in advance of the ambulance’s arrival, leading to more efficient care and improved patient survival.

Jaad Cabbabe, project leader for the MEDS team, explains that the “eureka” moment for the idea came during a discussion with a doctor who used to work in the emergency department at the Alfred Hospital in Melbourne. “The idea just clicked,” says Cabbabe.

“It offered a solution to a real problem that exists in hospitals and is not currently being addressed.”

Although ambulances in Australia use state-of-the-art ECGs with communication capabilities, the current technology doesn’t transmit patient data to doctors in advance of an ambulance’s arrival to hospital, which means doctors have to wait for vital patient information before they can formulate a diagnosis and treatment plan. Also, within hospitals ECGs are currently shared between doctors by fax or scanned photograph – methods that are neither efficient nor secure.

The ECGx/Medibase system transmits a patient’s ECG data to a central database, where medical professionals can access it, leading to a reduction in waiting times for diagnosis and treatment. The system has the capacity to save time, facilitate information sharing, improve consultations and decision-making, and allow doctors to more precisely target the needs of patients.

The ECGx/Medibase system is designed to be technology “agnostic”, or designed to to allow communication between the range of technologies currently being used by ambulances and hospitals.

The system won the prestigious Telstra University Challenge 2015: Connected World award in September. Cabbabe says the win has given the team a huge benefit through access to Telstra’s technical and commercial expertise and resources, helping them plan ahead, with the ultimate aim of commercialising the system. The team has also been invited to apply to muru-D, Telstra’s technology incubator, which provides upfront funds and state-of-the-art facilities for new technology start-ups.

The system is currently at the prototype stage, and requires further technical development before it can be considered for a field trial. “The next six months developing the working prototype will be key,” says Cabbabe. “But the real world application and the various [ECG] technologies we are proposing to work with is our biggest technical challenge.” The ECG technologies used in ambulances are not currently able to communicate with hospital systems, posing a technical challenge for the team.

Other challenges include navigating legal and regulatory hoops for medical devices, and passing their third year exams.

– Carl Williams